I'm not sure why you would want to run anything besides windows on NTFS. It's not a very good file system. You would be better off with EXT3, ReiserFS, or XFS as all are better than NTFS really, even if they do have some bugs. Any linux OS is going to be able to read FAT drives. If it's a system where you compile your own kernel, then just remember to include support for it. Ubuntu is likely the simplest linux OS. If you want a Windows look/feel, the Kubuntu would likely be a little better as KDE is more Windows-like than Gnome.