Not without getting complicated I don't think. You'd have to make the whole back park "deactivated."
You might have luck using a mask though. Put a un-clickable object (block) behind the top (larger) image that's partially or completely transparent, and that *might* block the hyperlinks on the other images.
Basically find a way to put a layer between the large zoomed image and the hyperlinked thumbnails.
"Greatness is not a function of circumstance. Greatness, it turns out, is largely a matter of conscious choice, and discipline." - Jim Collins